Wednesday, 21 October 2009
Swine Flu Vaccination Starts in Britain
Sky News 21/10/09
"Doctors have started the task of vaccinating millions of vulnerable patients against swine flu.
From Monday, GPs will receive their initial deliveries, though it could take up to four weeks to distribute the 4.5m doses around the country.
More will follow as it is delivered by the manufacturers.
Nine million patients who are at risk of serious complications if they catch the virus will be given priority for the vaccine.
At the front of the queue are those aged six months to 65 years who have underlying health problems such as asthma."
Next will be pregnant women, those living with patients with weakened immune systems, and finally the over-65s with underlying health problems."
The swine flu vaccination being introduced in Britain is Pandemrix from GlaxoSmithKline. This is from the GSK information for patients leaflet:
Pandemrix is a "split virion, inactivated, adjuvanted," vaccine, which means that only structural proteins from the virus are present and it is not infectious. (Flumist from Immumed, contains a live attenuated virus, which carries the risk of reverting to live in transmission.)
Split influenza virus, inactivated, containing antigen* equivalent to:
A/California/7/2009 (H1N1)v-like strain (X-179A)
3.75 micrograms** per 0.5 ml dose
* propagated in eggs
** expressed in microgram haemagglutinin
This vaccine complies with the WHO recommendation and EU decision
for the pandemic.
The vaccine contains an ‘adjuvant’ AS03 to stimulate a better response.
This adjuvant contains squalene (10.69 milligrams), DL-α-tocopherol
(11.86 milligrams) and polysorbate 80 (4.86 milligrams).
The other ingredients are: polysorbate 80, octoxynol 10,
thiomersal, sodium chloride, disodium hydrogen phosphate,
potassium dihydrogen phosphate, potassium chloride,
magnesium chloride, water for injections
You should not receive Pandemrix:
• if you have previously had a sudden life-threatening allergic reaction to
any ingredient of Pandemrix (these are listed at the end of the leaflet) or
to any of the substances that may be present in trace amounts as follows:
egg and chicken protein, ovalbumin, formaldehyde, gentamicin sulphate
(antibiotic) or sodium deoxycholate. Signs of an allergic reaction may
include itchy skin rash, shortness of breath and swelling of the face or
tongue. However, in a pandemic situation, it may be appropriate for
you to have the vaccine provided that appropriate medical treatment is
immediately available in case of an allergic reaction.
Very common (affects more than 1 user in 10)
• Pain, redness, swelling or a hard lump at the injection site
• Aching muscles, joint pain
Common (affects 1 to 10 users in 100)
• Warmth, itching or bruising at the injection site
• Increased sweating, shivering, flu-like symptoms
• Swollen glands in the neck, armpit or groin
Uncommon (affects 1 to 10 users in 1,000)
• Tingling or numbness of the hands or feet
• Diarrhoea, vomiting, stomach pain, feeling sick
• Itching, rash
• Generally feeling unwell
Rare (affects 1 to 10 users in 10,000)
Allergic reactions leading to a dangerous decrease of blood pressure,
which, if untreated, may lead to shock. Doctors are aware of this
possibility and have emergency treatment available for use in such cases.
• Severe stabbing or throbbing pain along one or more nerves
• Low blood platelet count which can result in bleeding or bruising
Very rare (affects less than 1 user in 10,000)
Vasculitis (inflammation of the blood vessels which can cause skin
rashes, joint pain and kidney problems)
• Neurological disorders such as encephalomyelitis (inflammation of the
central nervous system), neuritis (inflammation of nerves) and a type of
paralysis known a Guillain-Barré Syndrome
Squalene as an adjuvant.
According to Dr Russell Blaylock, a former neurosurgeon, squalene is added to boost the immune response to vaccines. The normal route by which an infectious agent enters the body is via the nose or the gut and this triggers a coordinated response from the immune system. When the infectious agent is injected into deep muscle, there is a need to include adjuvants to incite a response and this actually produces an abnormal response. Squalene is present in the body as a precursor to all the body's steroids. When injected into deep muscle, the immune system produces antibodies to squalene and attacks all the squalene in the body. 95% of vets returning from the Gulf, diagnosed with Gulf War Syndrome were reported to have tested positive for squalene antibodies.
Thiomersal as an adjuvant.
Thiomersal, or sodium ethylmercurithiosalicylate, commonly known in the United States as thimerosal, is an organomercury compound (approx. 49% mercury by weight) used as an antiseptic and anti-fungal agent, used as a preservative in vaccines.
Thiomersal is very toxic by inhalation, ingestion, and in contact with skin. In the United States, countries in the European Union and a few other affluent countries, thiomersal is no longer used as a preservative in routine childhood vaccinations. In the U.S., the only exceptions among vaccines routinely recommended for children are some formulations of the inactivated influenza vaccine for children older than two years.
Finally, from the American Journal Of Pathology
"The Endogenous Adjuvant Squalene Can Induce A Chronic T-Cell-Mediated Arthritis In Rats."
"Squalene is a cholesterol precursor, which stimulates the immune system nonspecifically. We demonstrate that one intradermal injection of this adjuvant lipid can induce joint-specific inflammation in arthritis-prone DA rats."
Read the entire article on the above link.